Scientific Leadership

In the rapidly evolving landscape of neonatal care and pediatric health, understanding the intricate interplay between nutrition, gut health, and the microbiome is paramount.  As neonatal nutrition continues to emerge as a critical determinant of long-term health outcomes, it is important to delve deep into the complexities of early life nutrition and its profound impact on gut development, immune function, and microbial colonization.

Early life Nutrition

Getting the right start early in life impacts a child’s lifelong health trajectory and immune resiliency. The first 1000 days of life, from conception through age two, is the most critical time for growth, brain development, and the creation of a strong immune system. It is a time of tremendous potential but also enormous vulnerability. Those first 1000 days present a unique window of opportunity for personalizing nutrition, care, and interventions.  

Peer-reviewed publications and scientific abstracts represent our exploration of the latest advancements in neonatal nutrition science, shedding light on novel insights, groundbreaking discoveries, and promising interventions aimed at optimizing the health and wellbeing of the youngest and most vulnerable population. These scholarly works offer invaluable contributions to the field, paving the way for innovative approaches to neonatal care and nutritional intervention.

Publication
Integrating longitudinal clinical and microbiome data to predict growth faltering in preterm infants.
Lugo-Martinez, J., Xu, S., Levesque, J., Gallagher, D., Parker, L., Neu, J., Stewart, C., Berrington, J. Embleton, N., Young, G., Gregory, K., Good, M., Tandon, A., Genetti, D., Warren, T. Bar-Joseph, Z. Journal of Biomedical Informatics 128 (2022) 104031.
Patents
U.S. Patent 10,811,126 B2, “System and Methods for Developing and Using a Microbiome-Based Action Component for Patient Health,” granted U.S., Canada, filed Dec 14, 2017.
17/ 074,173 “Systems and Methods for Developing and Using a Microbiome-based Action Component,” notice of allowance U.S., filed Oct 19, 2020.
17/194,070, “Predictive Microbial Biomarkers for Identifying Premature Infants Most Likely to Benefit from a Clinical Intervention,” pending, Mar 6, 2020
Scientific Presentations
Poster. Gomez Pomar, E.; Warren, T., Jantzen, T., Genetti, D.  “Faster increase of feedings in low birthweight (LBW) infants; feasibility, safety and monitoring of growth milestones with clinical decision support to improve compliance and metrics.” American Society of Parenteral and Enteral Nutrition Conference. Apr 2023.  Las Vegas, NV.

Poster.  Genetti, D., Xu, S., Lugo-Martinez, J., Bar-Joseph, Z., Parker, L., Neu, J., Tandon, A., Levesque, L., Gallagher, D., Warren, T. “Systematic evaluation of machine learning classification models to predict growth failure in preterm infants.” Pediatric Academic Societies May 2021.  Virtual. 

Poster.  Tandon, A., Genetti, D., Levesque, J., Alicea, A., Nayeem, A., Lee, K., Gallagher, D., Warren, T. “Visual narrative dashboard enables unique insights from longitudinal analysis of preterm infant gut microbiome, feeding, nutrition, and growth data.”  Hot Topics in Neonatology. Dec 2020.  Gaylord, MD.

Poster.  Tandon, A., Genetti, D., Levesque, J., Gallagher, D., Warren, T., La Reau, A., Smith, E., Jia, F., Adams, E., Ward, T.  “Using gut microbiome profiles to predict growth outcomes in preterm infants.”  Hot Topics in Neonatology. Dec 2020.  Gaylord, MD.

Poster. Beiting, D., Warren, T., Adams, E., Riquelme, V., Santiago-Rodriguez, T., Garoutte, A., Hollister, E.  “Stool microbiome composition reflects post-menstrual age in preterm infants and differs between infants with and without typical development.”  Presented at Pediatric Academic Societies. May 2020.  Virtual

Scientific Leadership

Building a Board

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Founder/Executive Transitions

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Activist Campaigns

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Adversarial Negotiations

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